KMID : 1094020140310020117
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Journal of Veterinary Clinics 2014 Volume.31 No. 2 p.117 ~ p.120
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A Case of Ependymoma in a Dog; Computed Tomography, Histopathological and Immunohistochemical Findings
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Lee Hee-Chun
Cho Kyu-Woan Jung Hae-Won Moon Jong-Hyun Kim Ji-Hyun Jung Dong-In Kim Na-Hyun Sur Jung-Hyang
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Abstract
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Abstract : An 11-year-old intact female Maltese was referred because of 1 week history of cluster seizure episodes. Based on brain CT scan, brain tumor was strongly suspected. The patient was euthanized according to client¡¯s requestand we performed necropsy after euthanasia. The gross findings of the postmortem coronal sections of the brain showedthat the mass was relatively well-demarcated, reddish in colored, and was present inside the left lateral ventricle andcompressed adjacent tissues. The tumor mass had 2 distinct histopathological features: perivascular pseudorosette-likestructures and a whirl-like arrangement of fibrillary cells. The immunohistochemical profile showed strong GFAPpositivity and moderate S-100 expression, sparsely dotted staining with Ki-67. Based on the histopathological andimmunohistochemical findings, the present case diagnosed to ependymoma.
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KEYWORD
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ependymoma, computed tomography (CT), dog
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